After striking back on Friday night, Iran launched a new wave of strikes toward Israel on Saturday morning. Now, the two countries continue to exchange deadly missiles and threats, with fatalities and injuries reported on both sides.

Israel's Prime Minister Benjamin Netanyahu says his country will strike "every site and every target of the ayatollah regime" in Iran.

U.S. officials told multiple outlets that the Navy directed the USS Thomas Hudner, a destroyer capable of intercepting ballistic missiles, from the western Mediterranean Sea toward the eastern Mediterranean Sea, where it will join the USS Arleigh Burke. A second destroyer was also ordered to change course to be available if requested.

Iran activated its air defences in several regions on Saturday and Israel told its citizens to take shelter ahead of a fresh barrage of missiles, as the arch-foes exchanged massive strikes in their fiercest direct confrontation in history.

Israel began carrying out a wave of strikes on Iran overnight, with the IDF saying it targeted nuclear sites and military chiefs. Revolutionary Guard chief Hossein Salami and other senior military figures have been assassinated, the IDF and Iran confirmed.

Shapiro served as Deputy Assistant Secretary of Defense for the Middle East until January—charged with, among other things, considering scenarios in which tensions between Israel and Iran escalated into all-out war and preparing U.

Iranian officials and lawmakers are warning of a withering Iranian retaliatory response against Israel but decision makers in Tehran may need to weigh up a major constraint: the desire to avoid actions that would bring the U.

James Anderson, former acting Under Secretary of Defense for Policy during the first Trump administration, told Newsweek what Iran's possible next steps may be.

U.S. Special Envoy Steve Witkoff plans to meet Iranian Foreign Minister Abbas Araghchi in Oman on Sunday and discuss Iran's response to a recent American proposal for a nuclear deal, a U.S. official said late on Wednesday.

US President Donald Trump urged Iran to accept a nuclear deal to avoid further attacks, hours after Israel bombed the Islamic Republic’s atomic facilities and killed some of its top commanders.