There are three AFC teams that will have full support for the 49ers when they face the Colts on Monday night. Three AFC teams ...

McCaffrey has a long injury history. If he's picked up a new knock, it's something that fans will naturally be concerned ...

The San Francisco 49ers have been dealt a tough injury hand in 2025, losing All-Pro defenders Fred Warner and Nick Bosa to season-ending injuries. Despite this, they've managed to remain a playoff ...

San Francisco 49ers running back Christian McCaffrey has been added to the injury report on Saturday with a back issue. ESPN's Adam Schefter has now provided more clarity of McCaffrey's status for ...

We may have seen the last of wide receiver Brandon Aiyuk in a San Francisco 49ers uniform. At least, that's what the team's ...

The Indianapolis Colts will officially have one of their most important defensive pieces back on the field for Week 16.

Ever since the blockbuster draft-order trade between San Francisco and Miami went down in late March, the glaring question has been this: Who will the 49ers select with their newly-acquired No. 3 ...

Gross-Matos (hamstring) was activated off the 49ers ' injured reserve list Monday, Adam Schefter of ESPN reports.

Brock Purdy lit up MNF for the 49ers against the Colts, throwing five touchdown passes and making history with a mark not ...

ESPN insider Adam Schefter has raised an interesting question about the San Francisco 49ers' quarterback situation heading into Week 10. However, Schefter wonders whether head coach Kyle Shanahan will ...

San Francisco 49ers running back Christian McCaffrey is putting together a season for the history books. While he's averaging a career-low 3.6 yards per carry, his versatility as a playmaker in both ...

The lines keep blurring between ESPN NFL insider Adam Schefter reporting news and giving opinions. Schefter, who often joins the network’s pregame shows as well as daytime programs like Get Up and The ...