Scientists at the Institute of Science Tokyo (Science Tokyo) have successfully realized the highly selective asymmetric 1,6 addition of aliphatic Grignard reagents to α,β,γ,δ-unsaturated carbonyl ...

SILICON tetrachloride forms 1 : 4, 1 : 2 and 1 : 1 addition compounds with amines. Only one monoaminate has been identified (silicon tetrachloride: dimethylaniline); but the tetraminates and the ...

Despite considerable advances, and the abundance of organometallic reagents developed for additions to carbonyl compounds, three key challenges have endured. First, the dependence on stoichiometric, ...

Compound libraries form a foundational element of modern drug discovery—the process of identifying new chemical or biological compounds that can become safe and effective medicines. Compound libraries ...