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Scientists uncover molecular mechanism behind chemotherapy-induced peripheral neuropathy
Chemotherapy activates a stress sensor in immune cells, triggering inflammation and nerve damage, which may help explain why ...
Patients suffering from so-called immune-mediated neuropathies frequently have a long medical record. As there are no diagnostic tests available to reliably diagnose the disease, the diagnosis is ...
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Restoring mobility: Rare autoimmune disease successfully treated with CAR T-cell therapy
A team of physicians from Bochum are the first to successfully use CAR T-cell therapy to treat two patients with a rare autoimmune disease of the peripheral nervous system. This treatment modifies ...
Kieseier and colleagues present a review of the literature on immune-mediated neuropathies, emphasizing the immunopathologic mechanisms underlying these neuropathies. Immune-mediated neuropathies have ...
An analysis of the medical records of patients treated at Massachusetts General Hospital (MGH) for an often-mysterious condition involving damage to small nerve fibers supports the hypothesis that ...
Expert Rev Clin Immunol. 2009;5(5):535-546. Owing to the role of DQ2 and DQ8 in the generation of gliadin-specific T cells in CS, it is thought that at some point, T cells specific for gliadin may ...
Autoimmune autonomic ganglionopathy (AAG) occurs when your immune system attacks healthy nerve cells in your autonomic nervous system. It causes symptoms like dizziness or faintness. Autoimmune ...
Researchers are working on an innovative approach to treat a rare autoimmune disease of the peripheral nervous system, using a kind of molecular sponge made of sugar to remove pathogenic antibodies ...
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