The pathogen C. diff—the most common cause of health care-associated infectious diarrhea—can use a compound that kills the human gut's resident microbes to survive and grow, giving it a competitive ...
Iron storage "spheres" inside the bacterium C. diff—the leading cause of hospital-acquired infections—could offer new targets for antibacterial drugs to combat the pathogen. A team of Vanderbilt ...
A new study from North Carolina State University shows that the inflammation caused by Clostridioides difficile (C. diff) infection gives the pathogen a two-fold advantage: by both creating an ...
Clostridium difficile is an unpleasant, sometimes severe, and potentially lethal infection. It is an enteric pathogen whose armory involves the production of a toxin leading to gut dysphoria and ...
"But when colonizing the gut, C. diff also produces two large toxins, TcdA and TcdB, which cause inflammation. We wanted to know if these inflammation-causing toxins actually give C. diff a survival ...
New study reveals at a molecular level how fidaxomicin selectively targets C. Diff bacteria while sparing the innocent bacterial bystanders of the gut microbiome. Most antibiotics are double-edged ...
A novel vaccination approach developed by Vanderbilt Health researchers cleared the harmful gut bacterium Clostridioides difficile (C. diff) in an animal model of infection. An experimental vaccine ...
Matthew Munneke, left, and Eric Skaar, PhD, MPH, use anaerobic chambers to study bacteria like C. diff that die in the presence of oxygen. The pathogen C. diff — the most common cause of health ...
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