Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, ...

Ruggiano and Ramadan 4 provide an overview of the mechanisms dedicated to removing replication obstacles, such as proteins covalently or tightly bound to DNA. Their work discusses how molecular ...