Objective Less than half of servicewomen report loss of menses during initial military training. However, self-reported menstrual status may not accurately reflect hypothalamic-pituitary-ovarian (HPO) ...

In order to maintain regular ovarian activity, the hypothalamus, pituitary, and the ovaries all have to function properly. Neurons that produce gonadotropin-releasing hormone (GnRH) are located in the ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

The HPO Axis is the body's hormonal control system that controls a woman's menstrual cycle, fertility, and reproductive health. It is essential for women's health. This blog discusses how it works, ...

Picking the Right Patient for Human Epidermal Growth Factor Receptor 3–Targeted Therapy in Platinum-Resistant Ovarian Cancer The Oncology Grand Rounds series is designed to place original reports ...

Please discuss the cause of ovulatory dysfunction in relation to subfertility. With anovulation, central defects (hypothalamic or pituitary) and ovarian failure have to be considered. Measurement of ...

Disruptions in hypothalamic–gonadal and other endocrine axes due to energy deficits are associated with low levels of the adipocyte-secreted hormone leptin and may result in hypothalamic amenorrhea.

Amenorrhea means an absence of menstruation. The term also applies to people who have not started their period by the age of 16, which is called primary amenorrhea. Secondary amenorrhea occurs in ...