Proximagen announced promising data from the pivotal Phase 3 trial of USL261 (intranasal midazolam) for the rescue treatment of seizure clusters. The primary efficacy endpoint was treatment success, ...

Nearly half of the children receiving intranasal midazolam for laceration repair in the emergency department (ED) exhibited extreme procedural anxiety. Younger age, reduced sociability, and extremity ...

For most people with epilepsy, seizures can be completely controlled by taking daily medication. However, some people still experience seizures despite taking daily medication. If these seizures recur ...

Intranasal midazolam is an effective alternative to the oral version for children undergoing dental treatments, according to a new study. Researchers found that when dentists administered the drug ...

Holsti and colleagues state that seizures lasting more than 5 minutes in the out- of-hospital setting are often treated by the patient's family. In the United States, rectal diazepam is the most ...

CAMBRIDGE, England, April 26, 2017 /PRNewswire/ -- Proximagen Limited (Proximagen) today announced that its pivotal Phase 3 trial of intranasal midazolam (USL261) for the rescue treatment of seizure ...

Patients treated with 5-mg midazolam nasal spray were more likely than those given placebo to remain seizure free for 6 hours after treatment or have their seizure terminated within 10 minutes, with ...

Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window Intranasal ...

The NDA includes data from the Phase 3 ARTEMIS 1 trial which evaluated the intranasal spray in 292 patients. The Food and Drug Administration (FDA) has accepted for review the New Drug Application ...

NAYZILAM® (midazolam) nasal spray CIV is a benzodiazepine indicated for the acute treatment of intermittent, stereotypic episodes of frequent seizure activity (i.e., seizure clusters, acute repetitive ...

Débora P. H. Schaffer, Nayone L. L. C. de Araújo, Ana Cláudia S. Raposo, Emanoel F. Martins Filho, João Victor R. Vieira and Arianne P. Oriá Safe and effective sedation protocols are important for ...