Analysis of the cases found that standard doses of both oral and intravenous macrolide administration were associated with SNHL. Results of a systematic review including 44 publications found that, ...

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Researchers captured and comparted hi-res images of ribosome structures from sensitive and resistant bacteria and report that a water molecule needed for antibiotic binding was not present in the ...

Research suggests bond duration, not bond tightness, may be the most important differentiator between antibiotics that kill bacteria and antibiotics that only stop bacterial growth. Research from the ...

Children of mothers prescribed macrolide antibiotics during early pregnancy are at an increased risk of major birth defects, and particularly heart defects, compared with children of mothers who are ...

Discovering antifungals with novel mechanisms of action is essential in the fight against drug-resistant fungi, which pose a serious concern for public health. However, progress on new antifungals is ...

The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome these resistances, drugs with novel modes of action are urgently needed.

As more and more pathogenic bacteria gain resistance to commonly used antibiotics, the search for new, effective, and safe antibiotics has become vital. According to The Lancet, almost 5 million ...