DeepTarget is a computational tool that integrates large-scale drug screens with omics data to predict mechanisms of cancer cell killing.

Understanding a drug’s mechanism of action (MOA) can greatly increase the likelihood of successful clinical trials by identifying biomarkers of patient response and providing a rationale for ...

The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome these resistances, drugs with novel modes of action are urgently needed.

Biomarkers are key to the development of biological drugs, offering vital insights into drug mechanisms of action (MOA), informing clinical study design, and optimizing treatment strategies.

Trypanosomatids are parasites that can result in more than 1 billion potentially fatal infections per year globally. In ...

Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published in Nature ...

Discover the emergence of dual-payload ADCs and PDCs, which could mark a significant evolution in targeted therapeutics.

M107 is the first potential disease-modifying drug for the treatment of gastroparesis -- M107's mechanism of action has been shown to shift pro-inflammatory M1 macrophages towards M2 anti-inflammatory ...