A new analysis shows that infectious bacteria exposed to the antibiotic albicidin rapidly develop up to a 1,000-fold increase in resistance via a gene amplification mechanism. A new analysis shows ...

Findings challenge the traditional view that antimicrobial resistance (AMR) emerges from pathogens that acquire new mutations. Samples from ICU patients suggest that instead, highly diverse pathogen ...

The discovery of a new mechanism of resistance to common antibiotics could pave the way for improved treatments for harmful ...

Scientists at St. Jude Children’s Research Hospital report a proof-of-concept study showing how antibiotic-resistant proteins can be exploited for the development of new antibiotics.

Scientists from the University of Illinois Urbana-Champaign have developed a method to isolate genes from amounts of microbial DNA so tiny that it would take 20,000 samples to weigh as much as a ...

The growing incidence of multidrug-resistant (MDR) or extensively-drug resistant (XDR) bacteria is an emerging challenge in modern medicine. Constant ...

Infectious diseases caused by pathogenic strains of bacteria are a global cause of morbidity and mortality. Hospital-acquired infections caused by Klebsiella pneumonia and Pseudomonas aeruginosa were ...

Two newly discovered mechanisms in bacteria have been identified that can contribute to the development of antibiotic resistance. Changing the number of copies of resistance genes in bacteria ...

Drug resistance remains the foremost challenge to durable cancer control. Tumors evolve dynamic mechanisms to evade therapy through target mutations, ...

As more and more bacteria develop resistance to the drugs designed to kill them, a new study has found that even a relatively new antibiotic isn’t immune. Researchers have uncovered a gene ...

Some lung cancers manage to overcome a targeted drug therapy despite it showing initial success. Yale researchers have now ...