Experimental data demonstrated that the lipid-lowering action of statins may partly explain beneficial effects of these drugs; the so called 'pleiotropic effects' of statins include inhibition of ...

J Gastroenterol Hepatol. 2012;27(11):1654-1664. Taken collectively, data summarized in this chapter are the molecular basis accounting for the findings observed both in animal studies and in humans ...

The cholesterol medication alirocumab, a PCSK9 inhibitor, combined with a statin appeared to reduce LDL cholesterol levels by more than 50% among patients after a heart transplant, according to a late ...

Atorvastatin, one of the world’s most widely prescribed cholesterol-lowering drugs, has played a major role in reducing heart disease rates in the United States. By blocking an enzyme responsible for ...

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