The emergence and rapid outbreak of a novel coronavirus, namely, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in China in 2019, caused a global pandemic, which is popularly known as ...

New research reveals that when gut bacteria closely resemble the myelin sheath that protects nerve fibers, the immune system can become confused and attack both — accelerating multiple sclerosis.

(L to R) Co-senior author Paul Thomas, PhD, and co-first author Robert Mettelman, PhD, St. Jude Department of Host-Microbe Interactions. The researchers found that a region of the SARS-CoV-2 ...

Edited by: Karen Young Kreeger K.W. Wucherpfennig, J.L. Strominger, "Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein," ...

If gut bacteria are too similar to the protective layer of nerves, they can misdirect the immune system and cause it to ...

A study reveals that pro-inflammatory gut bacteria mimicking the myelin sheath trigger immune attacks on nerves, worsening MS ...

The HLA influence and the fact that specific IgG production usually needs T cell help provides indirect evidence for a T cell ANO2 autoreactivity in MS. We propose a hypothesis where immune reactivity ...

Distinguishing between self and non-self is a critical ability of the immune system. Some pathogens have evolved proteins that resemble those of their host, a mechanism called molecular mimicry, in an ...

Background.Rheumatic heart disease (RHD) after group A streptococcus (GAS) infections is heritable and prevalent in Indigenous populations. Molecular mimicry between human and GAS proteins triggers ...

To continue reading this content, please enable JavaScript in your browser settings and refresh this page. Preview this article 1 min A new spinout of Cambridge ...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the coronavirus disease 2019 (COVID-19). SARS-CoV-2 is well known to cause severe respiratory illness in infected patients. However, ...