Single-Molecule Localization Microscopy (SMLM) has traditionally faced challenges to optimize signal-to-noise ratio, penetration depth, field-of-view (FOV), and spatial resolution simultaneously. Here ...

How do photosynthetic organisms harvest light so efficiently? To help answer this question, researchers have developed an ultrafast transient absorption microscope with sensitivity approaching the ...

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which garnered a Nobel Prize in 1953, brought into clear view structures inside ...

Light field microscopy (LFM) is a revolutionary technique first introduced in 2006 which can essentially capture a 3D volume in a single snapshot, complete with digital refocusing and deconvolution.

Recent years have witnessed the fast growth of super-resolution microscopy (SRM) methods based on the mass accumulation of single-molecule positions, i.e., single-molecule localization microscopy ...

At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules. DNA is a molecule found in just about every living cell. Because ...

Standard genetic sequencing approaches can tell you a lot about the genetic makeup and activity in a sample, like a piece of tissue or drop of blood. But they don't tell you where specific genetic ...

(Nanowerk News) Researchers at the University Medical Center Göttingen (UMG), Germany, have developed a new method that makes it possible for the first time to image the three-dimensional shape of ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Both for research and medical purposes, researchers have spent decades pushing the limits of microscopy to produce ever deeper and sharper images of brain activity, not only in the cortex but also in ...

Listed in the Guinness World Records, this tiny electric motor needs a special kind of microscope capable of making out a ...