Treatment of nonfunctioning neuroendocrine tumors with somatostatin analogs has been controversial, given the low antitumor effects of these drugs. The PROMID study group now reports that octreotide ...

Malignant pleural mesothelioma (MPM) is an aggressive neoplasm arising from mesothelial lining of pleura. CD26 molecules preferentially expressed on epithelioid type of MPM. This study investigates ...

Phase III Comparison of Vitespen, an Autologous Tumor-Derived Heat Shock Protein gp96 Peptide Complex Vaccine, With Physician's Choice of Treatment for Stage IV Melanoma: The C-100-21 Study Group Well ...

Endoscopic retrogade cholangiopancreatography is essential for the diagnosis and therapy of biliary and pancreatic diseases. Complications are relatively frequent, amongst which pancreatitis is the ...

Grafton Therapeutics Sarl has identified halogenated somatostatin analogues acting as somatostatin SST2 receptor and/or SST5 receptor agonists reported to be useful for the treatment of cancer.

Overall survival (OS) in patients with EGFR-mutated new diagnosed stage IIIB/IV NSCLC in addiction of exon 19, 18/20 and 21 mutation and in addiction of treatment with tyrosine kinase inhibitor (TKI) ...

A model for a biologically active conformation of somatostatin is proposed. This model is based primarily on the biological results obtained with novel bicyclic somatostatin analogs having a covalent ...

This is a preview. Log in through your library . Abstract Recently, considerable interest has been aroused by the specific actions of bisphenol A (BPA). The present investigation represents a first ...

Patients with diabetes have high blood glucose levels either because their pancreas does not produce sufficient insulin, or their body cells do not respond to signals from insulin that tell them to ...

The US Food and Drug Administration (FDA) has approved oral octreotide (Mycapssa, Chiasma) delayed-release capsules for the long-term maintenance treatment of patients with acromegaly who previously ...

An international team of researchers headed by scientists at the University of Copenhagen has discovered that venoms produced by one group of fish-hunting deep sea cone snails contain compounds ...

Scientists are finding clues for how to treat diabetes and hormone disorders in an unexpected place: a toxin from one of the most venomous animals on the planet. A multinational research team led by ...