Researchers have confirmed that neuropeptide somatostatin can improve cognitive function in the brain. A research group of Professor Seung-Hee Lee from the Department of Biological Sciences at KAIST ...

Somatostatin, a signaling molecule produced by many inhibitory neurons in the brain, broadly dampens communication among a variety of cell types in the prefrontal cortex and promotes exploratory and ...

Objective: Somatostatin (SST) is secreted by islet δ-cells and by extraislet neuroendocrine cells. SST receptors have been identified on α- and β-cells, and exogenous SST inhibits insulin and glucagon ...

Different types of interneurons are important in shaping cortical information processing; however, the mechanisms by which they regulate sensory coding is unclear. Inhibition is typically proposed to ...

Excitation–inhibition balance is critical for optimal brain function, yet the mechanisms underlying the tuning of inhibition from different populations of inhibitory neurons are unclear. Here, we ...

Chemokine Receptor CXCR4 Expression in Colorectal Cancer Patients Increases the Risk for Recurrence and for Poor Survival One patient developed renal insufficiency, and another patient developed ...

Somatostatin analogues are medicines that stop your body from making too many hormones. Some neuroendocrine tumours (NETs) make large amounts of hormones. This can cause symptoms. Somatostatin ...

Tirapazamine, Cisplatin, and Radiation Versus Fluorouracil, Cisplatin, and Radiation in Patients With Locally Advanced Head and Neck Cancer: A Randomized Phase II Trial of the Trans-Tasman Radiation ...

What am I looking at? This image shows a 1-millimeter-thick coronal slice (from top to bottom) through the brain of a mouse, with neurons that produce somatostatin in purple (1) and pyramidal neurons ...

This may look like an abstract work of art, with bold splashes of purple paint. In fact, the purple areas in this image are cells that make the neurotransmitter somatostatin, which is produced all ...