A new study led by Baylor College of Medicine identifies an underlying mechanism of pathogenesis for osteogenesis imperfecta (OI) in human bone. The report, published in the Journal of Clinical ...

On Target is a new recurring feature from STAT that dives deep into the most promising drug targets in oncology. Of all the wily ways tumors have to turn back attacks from therapies or the immune ...

Spinal cord injury (SCI) often leads to long-term loss of motor and sensory function, with limited available treatment options to restore the lost ...

TGF-ß, which has been studied for more than 30 years, has many jobs. One of them is helping to regulate the immune system. The immunotherapy drugs called checkpoint inhibitors have transformed ...

Transforming growth factor-β (TGF-β) signaling plays a vital role in regulating cell growth, differentiation, and development in a wide array of biological systems. Members of the TGF-β family play a ...

When it comes to cancer metastasis, it takes two to tango. That was one of the key findings of a new study led by researchers at Memorial Sloan Kettering Cancer Center (MSK): The TGF-beta and RAS ...

If biology did have a motto, it may well be ‘nothing is ever as simple as it seems,’ an idea which is exemplified by today’s scientific story. It comes to us from the Prlic Lab in the Vaccine and ...

IO Biotech announced promising findings regarding a novel peptide vaccine designed to counter the immunosuppressive effects of Transforming Growth Factor Beta (TGF-β) in solid tumors. The research, ...