Diuretic therapy remains a vital cog in the management of hypertension; either as monotherapy or in combination with other antihypertensive classes. However, maximizing the antihypertensive effect of ...

Thiazide-type diuretics reduce the risk for mortality, stroke, and cardiovascular disease among patients with hypertension. 1 Given the reasonable adverse effect profile and high-quality evidence for ...

In the chronic response phase of therapy the vasodepressor influence of a diuretic emerges as a process driven by a reduction in total peripheral resistance (TPR), which is inadequately explained ...