Three reactions diversify antibody genes in human somatic cells of the B lineage: VDJ recombination, somatic hypermutation and class-switch recombination. The discovery of activation-induced cytidine ...

Scientists have developed a new tool that can rapidly estimate the number of T cells (immune cells) in a cancerous tumor. With T cell abundance helping predict a patient's response to immunotherapy, ...

Researchers have taken an in-depth look at the gene shuffling process that is responsible for our body's ability to recognize a vast range of foreign agents such as disease-causing microorganisms ...

Arguably the most critical characteristic of the immune system is its ability to adapt following immune exposures. T cells are an exquisitely specific cells that are “trained” to hunt down infection ...