The crash happened shortly before 3 a.m., just south of Laurel Street, according to the California Highway Patrol.

A fatal two-vehicle crash caused a temporary shutdown on southbound Interstate 5 near downtown San Diego early Friday morning ...

The wrong-way crash involved a Dodge and a Honda, the CHP said. One man died at the scene, the other at a nearby hospital.

A pre-dawn wrong-way crash on Interstate 5 near San Diego International Airport left two people dead today, after one vehicle slammed head-on into another and erupted in flames, shutting down the ...

Two people were killed early Friday in a wrong-way crash on Interstate 5 near San Diego International Airport.

All southbound lanes of Interstate 5 north of Palm Avenue in the South Bay have been shutdown due to a crash, causing ...

You are watching a live feed of NBC 7 News Today at 6 a.m. This story will be mixed with weather, traffic and other top stories. Two people were killed Friday morning when a wrong-way driver collided ...

SAN CLEMENTE, Calif. (FOX 5/KUSI) — U.S. Border Patrol agents assigned to the San Diego Diego Sector seized nearly $1.5 million worth of cocaine during a traffic stop along Interstate 5 in San ...

SAN DIEGO (KGTV) — A police pursuit shut down Interstate 5 southbound at Palomar Street for about three hours on Saturday. The California Highway Patrol responded to the police pursuit, and they found ...

A late-night crash on one of San Diego’s busiest freeways produced a scene so unusual that even veteran first responders were left speechless. Two vehicles ended up overturned and wedged on top of ...

Traffic was delayed for several hours Thursday morning when a big rig overturned on Interstate 5 near Mission Bay Drive. The crash happened around 4:40 a.m. Thursday on southbound I-5 near Mission Bay ...

Caltrans will close all lanes of southbound State Route 163 from Interstate 8 to Interstate 5 on Saturday, May 9, from 3 a.m. to 1 p.m. for maintenance work, impacting several connecting ramps and ...