The emergence and rapid outbreak of a novel coronavirus, namely, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in China in 2019, caused a global pandemic, which is popularly known as ...

New research reveals that when gut bacteria closely resemble the myelin sheath that protects nerve fibers, the immune system can become confused and attack both — accelerating multiple sclerosis.

The HLA influence and the fact that specific IgG production usually needs T cell help provides indirect evidence for a T cell ANO2 autoreactivity in MS. We propose a hypothesis where immune reactivity ...

To continue reading this content, please enable JavaScript in your browser settings and refresh this page. Preview this article 1 min A new spinout of Cambridge ...

Edited by: Karen Young Kreeger K.W. Wucherpfennig, J.L. Strominger, "Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein," ...

If gut bacteria are too similar to the protective layer of nerves, they can misdirect the immune system and cause it to attack its own nervous system. This mechanism can accelerate the progression of ...

Background.Rheumatic heart disease (RHD) after group A streptococcus (GAS) infections is heritable and prevalent in Indigenous populations. Molecular mimicry between human and GAS proteins triggers ...

Distinguishing between self and non-self is a critical ability of the immune system. Some pathogens have evolved proteins that resemble those of their host, a mechanism called molecular mimicry, in an ...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the coronavirus disease 2019 (COVID-19). SARS-CoV-2 is well known to cause severe respiratory illness in infected patients. However, ...

What if the enemy attacking the brain is not a virus, a toxin or an external threat—but a look-alike living quietly inside the gut? New research from the University of Basel suggests that certain gut ...