Renal denervation (RDN) has increasingly gained attention in cardiovascular medicine as a potentially transformative approach ...

The REMODEL trial testing semaglutide’s efficacy in patients with CKD and T2DM also employed MRI, transcriptomics, blood and urine samples, and kidney biopsies to clarify the drug’s effects.

Chronic kidney disease has surged to nearly 800 million cases and is now among the top causes of death worldwide. The ...

Objectives Heart failure (HF), chronic kidney disease (CKD) and atherosclerotic cardiovascular disease (ASCVD) are highly prevalent conditions that often coexist. Using electronic health records (EHRs ...

Sudden weight fluctuations significantly impact kidney health, increasing the risk of chronic kidney disease progression and reduced function. Both rapid weight gain, often due to fluid retention, and ...

Chronic kidney disease (CKD) is a progressive condition in which the kidneys gradually lose their ability to filter waste from the blood. It is a common health concern that affects an estimated 8–16% ...

Most cases of immunoglobulin A (IgA) nephropathy are sporadic (or idiopathic), occurring over time for reasons experts don't fully understand. Research suggests that genetic factors are involved in ...

Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental factors, as well as existing medical conditions. Known genetic risk factors for ...

- By examining over 100 unique variants associated with the CASR gene causative of ADH1, the average frequency of gain-of-function CASR variants was ~3.7 per 100,000, closely aligned to previously ...