A huge storm system crossing the U.S. threatens to unleash tornadoes Friday in the Mississippi Valley, blizzards in the northern Plains and dry, gusty conditions in Texas and Oklahoma that pose an extreme risk of wildfires.

A powerful storm dropping drenching rain on flood-prone Southern California is raising concern among forecasters that it could produce a dangerous, widespread outbreak of tornadoes, damaging winds and fires along with a blizzard as it crosses the entire United States in the coming days.

More than 100 million people in the U.S. will be in the path of an intense March storm starting Friday as the sprawling multi-day system threatens fires, blizzards, tornadoes, and flooding as it tracks eastward across the Great Plains.