Background Overexpression of the transforming growth factor β family signalling molecule smad2 in the airway epithelium provokes enhanced allergen-induced airway remodelling in mice, concomitant with ...

1 Department of Pulmonary and Intensive Care Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands 2 Department of Biostatistics, Erasmus Medical Center Rotterdam Correspondence to: ...

Division of Respiratory and Critical Care Medicine, Department of Medicine, Queen’s University, Kingston, Ontario, Canada Correspondence to: Dr D E O’Donnell Division of Respiratory and Critical Care ...

1 Department of Thoracic Surgery, School of Medicine, Akdeniz University, Antalya, Turkey 2 Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey 3 Department of Histology ...

1 Clinical Trials Research Unit, The University of Auckland, Auckland, New Zealand 2 Liggins Institute, The University of Auckland, Auckland, New Zealand 3 Department of Medicine, The University of ...

Background Pulmonary microvasculature alterations are implicated in emphysema pathogenesis, but the association between ...

A structural and metabolic framework for classifying pre-clinical tuberculosis infection phenotypes using 18F-FDG PET-CT: a prospective cohort analysis following M. tuberculosis exposure ...

1 Department of General Practice, Division of Public Health, Academic Medical Center, University of Amsterdam, The Netherlands 2 Department of Clinical Epidemiology, Leiden University Medical Centre, ...

BACKGROUND Pulmonary rehabilitation programmes improve the health of patients disabled by lung disease but their cost effectiveness is unproved. We undertook a cost/utility analysis in conjunction ...

Background: Inhalation of hypertonic or even isotonic saline during sputum induction may cause bronchospasm in susceptible patients with asthma, despite premedication with 400 µg inhaled salbutamol ...

Introduction Oral pirfenidone reduces lung function decline and mortality in patients with idiopathic pulmonary fibrosis (IPF). Systemic exposure can have significant side effects, including nausea, ...